Prevalence of Reactive HBsAg in Pregnant Women at Binanga Health Center, Mamuju Regency

Abbas Mahmud, Nurdiana Nurdiana, Riski Dyah Haninggar, Irmawati Irmawati

Abstract


Hepatitis B virus infection is an infectious disease caused by the Hepatitis B virus which is a global problem. It is estimated that more than 240 million people have been infected and every 620,000 people die from hepatitis B infection every year. Pregnant women range from Hepatitis B infection, can result in an increased risk of preterm birth, low birth weight (<2500 g), premature rupture of membranes, gestational diabetes, congenital abnormalities. Other consequences are miscarriage, liver damage, acute Hepatitis, or chronic, hepatocellular carcinoma. This   aims of this study was determine the incidence of reactive pregnant women from the rapid test of HBsAg. Methods: This study was  a descriptive observational study, by collecting data from the 2018 HBsAg examination sheet. The data sheet is the result of routine HBsAg examination in pregnant women Binanga Health Center, Mamuju Regency. . The independent variables identified were characteristic and sociodemographic data. Descriptive statistical tests were carried out in the form of frequency, percentage. The number of pregnant women who were reactive to HBsAg was 13 (2%) of 647 pregnant women throughout 2018, among those who were reactive were aged 20-30 years. However, pregnant women who are reactive to HBsAg are around the age of 20-30 years. The prevalence of reactive HBsAg in pregnant women in the Binanga Community Health Center is 13(2%). 


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Geda YF, Desse H, Gesesse MM, Berhe TM. Hepatitis B surface antigen and associated factors among mothers who had antenatal care contact in Attat Hospital, southern Ethiopia. SAGE Open Med. 2021;9(January 2020):205031212110244.

Gerlich WH. Medical Virology of Hepatitis B: How it began and where we are now. Virol J [Internet]. 2013;10:239. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729363/

Komatsu H. Hepatitis B virus: Where do we stand and what is the next step for eradication? World J Gastroenterol. 2014;20(27):8998–9016.

Dunkelberg JC, Berkley EMF, Thiel KW, Leslie KK. Hepatitis B and C in pregnancy: A review and recommendations for care. J Perinatol. 2014;34(12):882–91.

Han GR, Xu CL, Zhao W, Yang YF. Management of chronic hepatitis B in pregnancy. World J Gastroenterol. 2012;18(33):4517–21.

Silasi M, Cardenas I, Kwon JY, Racicot K, Aldo P, Mor G. Viral Infections During Pregnancy. Am J Reprod Immunol. 2015;73(3):199–213.

Data A. KASL clinical practice guidelines for management of chronic hepatitis B. Clin Mol Hepatol. 2019;25(2):93–159.

Xu C, Liu J, Liu L, Bi Y, Xu B, Chen J, et al. Comparison of hepatitis B viral loads and viral antigen levels in child-bearing age women with and without pregnancy. BMC Pregnancy Childbirth. 2018;18(1):1–8.

Cui AM, Cheng XY, Shao JG, Li HB, Wang XL, Shen Y, et al. Maternal hepatitis B virus carrier status and pregnancy outcomes: A prospective cohort study. BMC Pregnancy Childbirth [Internet]. 2016;16(1):1–9. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845477/

Chang MH, Chen DS. Prevention of hepatitis B. Cold Spring Harb Perspect Med [Internet]. 2015;5(3):1–8. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355249

Karnsakul W, Schwarz KB. Hepatitis B and C. Pediatr Clin North Am. 2017;64(3):641–58.

Dakl AAA, Alnuaimy WA. Epidemiology of hepatitis B and C in Al-Muthanna province. Indian J Forensic Med Toxicol. 2020;14(2):492–4.

Girawan D, Judistiani RTD, Risan NA, Bestari MB, Nugraha ES, Ermaya YS, et al. The High Prevalence of Negative Hepatitis B Surface Antibody (Anti-HBs) among Pregnant Women in Bandung, Indonesia: A Community-Based Study. Int J Hepatol. 2020;2020:1–11.

Virine B, Osiowy C, Gao S, Wang T, Castillo E, Martin SR, et al. Hepatitis B virus (HBV) variants in untreated and tenofovir treated chronic hepatitis B (CHB) patients during pregnancy and post-partum follow-up. PLoS One [Internet]. 2015;10(10):1–9. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608582/

Zhang Y, Chen J, Liao T, Chen S, Yan J, Lin X. Maternal HBsAg carriers and pregnancy outcomes: a retrospective cohort analysis of 85,190 pregnancies. BMC Pregnancy Childbirth. 2020;20(1):1–16.

Adams Waldorf KM, McAdams RM. Influence of infection during pregnancy on fetal development. Reproduction. 2013;146(5):1–2.

Eke AC, Eleje GU, Eke UA, Xia Y, Liu J. Hepatitis B immunoglobulin during pregnancy for prevention of mother-to-child transmission of hepatitis B virus. Vol. 2017, Cochrane Database of Systematic Reviews. 2017.

Biondi MJ, Marchand-Austin A, Cronin K, Nanwa N, Ravirajan V, Mandel E, et al. Health services: Prenatal hepatitis b screening, and hepatitis b burden among children, in ontario: A descriptive study. Cmaj. 2020;192(43):E1299–305.

Dortey BA, Anaba EA, Lassey AT, Damale NKR, Maya ET. Seroprevalence of Hepatitis B virus infection and associated factors among pregnant women at Korle-Bu Teaching Hospital, Ghana. PLoS One. 2020;15(4):1–13.

Al-Busaf S, Al-Harthi R, Al-Naamani K, Al-Zuhaibi H, Priest P. Risk Factors for Hepatitis B Virus Transmission in Oman. Oman Med J. 2021;36(4):e287–e287.

Dagnew M, Million Y, Gizachew M, Eshetie S, Yitayew G, Asrade L, et al. Hepatitis B and C Viruses’ Infection and Associated Factors among Pregnant Women Attending Antenatal Care in Hospitals in the Amhara National Regional State, Ethiopia. Int J Microbiol. 2020;2020:1–20.

Abbas Z, Abbas M. Challenges in Formulation and Implementation of Hepatitis B Elimination Programs. Cureus. 2021;13(4):1–9.




DOI: https://doi.org/10.32382/uh.v3i1.2469

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